This research delves into the evolving strategies for effectively communicating genetic information. Specifically, it explores health communication strategies as tools for enhancing health literacy. With the burgeoning role of digital media in disseminating public service messages, there is a growing emphasis on digital journalistic practices within health Vodcasts. However, despite the potential of health Vodcasts to promote preventive health behaviors against genetic disorders, their precise impact remains unclear. To address this gap, the study employs content analysis of health frames within digital health Vodcasts from popular media outlets in Pakistan. This research sheds light on journalistic practices related to genetic diseases, their preventive measures, and pre-marital screening. The findings reveal the prominence of the Health Severity frame, followed by the Consequence and Human-interest Frame, in Health Vodcasts. By advocating for more persuasive health campaigns on public health issues, this study contributes to advancing the field of health communication.